Do you ever wonder how your physician chooses a suitable medication for you? Do you feel overwhelmed by sheer number of available medications? These tips will help you understand the choices that are available. In subsequent articles, there will be more information about each class of medication.
While there are hundreds of medications and combos of medications available, there are 7 different classes of medication. Every class works in a different way. Your physician utilizes his knowledge about you as well as your specific type of diabetes to first decide if you need any medication, and if therefore , which class to use. He then selects a medication from that course. If you require medication from more than one class he may choose to prescribe several medication or a combination pill that has two or more medications contained in it. This article will provide a brief overview of the courses of medications and how they work.
1 . ) The oldest course of medication is the sulfonylureas. Till the mid-1990s, this was the only class of oral medications available. Your body must be able to produce insulin in order for these types of to be beneficial, as they work by stimulating the beta cells of the pancreas to secrete insulin. Some examples of the first generation of these medications are: Tolbutamide (orinase), Tolinase (tolazamide), and Diabinese (chlorpropamide). Some of the 2nd generation medications are: Glipizide (glucatrol), extended release Glipizide (glucatrol XL), Glyburide (Micronase, Diabeta), Glynase (micronized glyburide), and Glimepiride. These medicines are distinguished by how long these people last in the body, and whether they are cleared by the kidney or the liver organ. There are two other drugs in this class: Prandin and Starlix, which may be used before meals because they final for a very short time.
2 . ) The biguanide class has just 1 medication, called Metformin. Other names are Fortamet, Glucophage, Gluymetza, and Riomet. This medication works by reducing glucose production in the liver, and in addition it causes a small increase in glucose subscriber base by skeletal muscle. If you will find no contraindications, the American Diabetes Association as well as the American college associated with clinical endocrinologists recommends using this medication first.
3. ) In the mid-1990s, the Thiazolidinedione class of medications (also known as glitizones or TZDs) was developed. Their primary mechanism of action is to increase insulin awareness, which leads to more glucose being taken up by skeletal muscle. Three medications were developed. The first, Rezulin (troglitazone), was taken off the market since it was suggested to cause liver organ problems.
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The second, Avandia (rosiglitazone), has been withdrawn from the market in Europe but was allowed under selling restrictions in the US because of an increase in cardio events. The third medication, Actos (pioglitazone) had sales suspended in France and Germany because a study recommended it may increase the risk of bladder cancer.
4. ) Drugs that affect the incretin system are separated into two subclasses:
a. The first division is composed of injectable drugs which usually mimic the effect of natural incretins produced by the body. Medications in this course include Byetta (exenetide), Bydureon (long acting exenatide) Victoza (liraglutide), and Symlin. They work by improving insulin secretion in response to glucose (sugar), decreasing the rate at which the liver organ puts out glucose, decreasing appetite, and by slowing the rate the stomach empties. These medications have become quite popular simply because they can help with weight loss, and have an extremely reduced incidence of hypoglycemia. However , these medications have been in the news because they have been associated with pancreatitis, and may lead to a small increase in medullary thyroid cancer.
w. The oral medications in this course work by blocking the chemical which breaks down the incretins. As the level of natural incretins increases considerably, these drugs are not as effective as the injectable ones. Medications in this class include Januvia (sitagliptin), Onglyza (saxagliptin), and Tradjenta. They are getting observed to watch out for complications similar to the injectable medications. They very rarely trigger hypoglycemia and do not cause weight gain. All of them are being evaluated for a potential malignancy risk.
5. ) There are 3 Alpha Glucosidase Inhibitors: Acarbose (Precose), Miglitol (Glyset), and Voglibose. These types of work by preventing digestion of carbohydrates in the intestine. By stopping carbohydrates from being converted into basic sugars and absorbed into the blood stream from the intestine, this class associated with medications can help keep the blood sugar through rising after meals.
6. ) The newest class of medications may be the SGLT2 inhibitors, which block intake of glucose by the kidney. Simply by increasing the amount of glucose lost with the urine, and decreasing the amount of glucose absorbed back into the blood stream, blood sugar may be decreased. Because none of these medications has been approved by the FDA, the names of the medications are omitted from this article.
7. ) Insulin must be used for people with type I Diabetes and is often needed for those with kind 2 Diabetes. There are many types and delivery systems which will be discussed eventually.
With a thorough understanding of your specific type of diabetes, your physician can wade by means of all the options to select the best go with for you. More detailed information about each drug class will be presented in following articles here, and on my web site, diabeticsurvivalkit. com. Please feel free to go to at any time for information about medications, food preparation videos featuring diabetic meal and dessert recipes, and current news articles.
And now, Dr . Kramer attracts you to her website, which the lady operates with her daughter Tova. There, you will find cooking videos offering recipes appropriate for people with diabetes, a blog containing diabetes news along with other interesting content, and the ability to connect directly with Dr . Kramer. The girl and her daughter would like to understand how they can serve you!